“Mutations in DNA are closely tied to cancer and other diseases, and thus mutagenic substances can have dire effects on human health”.
Scientists across the U.S. and the rest of the world have sought to rigorously test any possible toxicity caused by GMOs. Some experiments on humans would be completely unethical. Fortunately, prior to these studies years of work have demonstrated that rodents, like mice and rats, are acceptable models for humans, meaning rodent responses to drugs, chemicals, and foods can predict human response. Although scientists have been able to demonstrate that GMOs are not toxic to the animals that eat them, what about side effects being passed on to our next generations?. A group from South Dakota State University monitored the GMO-eating rats not only for the lifetime of one generation, but also three additional generations. The group found no change in testicular health or litter sizes in any generation. Likewise, ingestion by pregnant mothers had no effect on fetal, postnatal, pubertal, or adult testicular development of her offspring. Other groups have monitored toxicity over time as well. For example, the group studying the bar GMO potato also wanted to see if organs and reproductive health were sensitive to GMOs over long exposure times suggesting that there is no buildup or inheritance of toxicity, even over multiple generations. Concern has also surrounded the idea that genetically modified DNA would be unstable, causing damage (via unintentional mutations) not only to the crop, but also to whomever would consume it. Mutations in DNA are closely tied to cancer and other diseases, and thus mutagenic substances can have dire effects on human health.